Familial Aggregation of Stroke
نویسنده
چکیده
Stroke is the second leading cause of death worldwide, and the leading cause of acquired disability in adults in most regions. Fifteen million people worldwide suffer a stroke each year with devastating effects; one third of these individuals die and another one third remains permanently disabled. However, there is a considerable additional unreported asymptomatic cerebrovascular disease. According to the literature, MRI-defined silent brain infarcts can be detected in 20% of healthy elderly 1-3 people and up to up to 50% of patients in selected series.
منابع مشابه
Familial aggregation of ischemic stroke in young women: the Stroke Prevention in Young Women Study.
BACKGROUND AND PURPOSE Stroke occurs infrequently in young adults. While a familial basis for older onset stroke is well established, the extent of familial clustering in young-onset stroke is unknown. To address this issue, we compared the frequency of stroke in relatives of stroke cases to that in relatives of controls across different ages and by stroke subtype. METHODS Through a populatio...
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BACKGROUND AND PURPOSE Family history is perceived to be an important risk factor for stroke despite conflicting published data. We examined patterns of familial aggregation of stroke among three generations using data from the Framingham Study. METHODS Cox proportional hazards analyses, adjusting for known stroke risk factors, were used to examine familial concordance in three groups: (1) me...
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Background and Aim: The aim of this study is to evaluate the familial aggregation of esophageal cancer in a defined population under coverage of Babol Research Station, Institute of Public Health Research, Tehran University of Medical Sciences, in one of the high incidence areas in north of Iran and to assess the risk of disease associated with first degree familial relationship. Material and ...
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Introduction & Objective: Stroke is the third cause of death in developed countries and the most common neurologic disease resulting in disability. Nowadays, several risk factors for stroke are recognized properly. Life style and risk factors such as hypertension and diabetes are different among various cultures and countries. This study was designed to evaluate strokes epidemiology and their c...
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BACKGROUND A familial occurrence of intracranial aneurysms is defined by the presence of such aneurysms in two or more first to third-degree family members. Families with two affected members may represent accidental aggregation. Other families show a frequency compatible with an autosomal dominant mode of inheritance. A genetic basis is also suggested by the younger average age of familial cas...
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Anti-platelet agents such as aspirin and dipyridamole are main factors to prevent stroke in high-risk people. Pentoxyphiline has been reported as a red blood cell aggregation antagonist to prevent stroke. We evaluated the role of pento-xyphiline as an adjunct therapy to decrease risk of stroke in patients who were under treatment with aspirin or dipyridamole. A 5-years open labeled clinical tri...
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تاریخ انتشار 2014